08:30 – 10:00
Registration
Set-up of posters and exhibition area
10:00 – 10:15
Welcome Address
10:15 – 10:55
PLENARY LECTURE I
Chair: José Belo
Stem Cells Models of Cardiac Development and Disease
Ibrahim Domian – Cardiovascular Research Center at the Massachusetts, General Hospital, USA.
10:55 – 11:25 – COFFEE BREAK
11:25 – 13:00 – SESSION 1. Stem Cells and Development
Chair: Perpétua Pinto-do-Ó and Inês Araújo
11:25 – 11:50
INVITED SPEAKER 1 – António Jacinto- CEDOC
Regulation of tissue growth during Zebrafish caudal fin regeneration through the Hippo pathway
Rita Mateus, Gonçalo Brito, Fábio Valério, António Jacinto
11:50 – 12:15
INVITED SPEAKER 2 – José Bragança – UALG/CBME
CITED2 supports stemness of embryonic stem cells.
José Bragança
12:15 – 12:30
Hes5 mediates cardiac specification while negatively regulating primitive hematopoiesis
AG Freire, A Waghray, TP Resende,DF Lee, J Su, CF Pereira, DS Nascimento, P Pinto-do-Ó & IR Lemischka
12:30 – 12:45
Regulation of Neurogenesis-induced Mitochondrial Damage by p53
JM Xavier, AL Morgado, S Solá and CMP Rodrigues
14:15 – 14:55
PLENARY LECTURE II
Chair: Nuno Neves
Skeletal stem cell based strategies for bone regeneration: Translation from bench to clinic
Richard Oreffo – Institute of Developmental Sciences, University of Southampton, UK.
14:55 – 16:15 – SESSION 2. Tissue Engineering
Chair: Gabriela Silva and Cláudia Lobato
14:55 – 15:20
INVITED SPEAKER 3 – Manuela E. Gomes – UMinho/3B’s
Stem Cells and Platelets lysates as key elements in the development of autologous human skeletal tissue substitutes
Manuela E. Gomes
15:20 – 15:45
INVITED SPEAKER 4 – Pedro L. Granja – INEB
Engineering stem cell fate through cell-matrix interactions
CC Barrias, KB Fonseca, FR Maia, SJ Bidarra, Pedro L Granja
15:45 – 16:00
3-D suspension cultures of umbilical cord-derived mesenchymal stromal cells(UCX®): preservation of mesenchymal properties and potential for skin regeneration
M Santos, E Filipe, M Filipe, M Teixeira, M Cipriano, R Barcia, P Cruz, D Mosqueira, DS Nascimento, P Pinto-do-Ó, H Cruz, M Castro, JP Miranda
16:00 – 16:15
Nerve regeneration using mesenchymal stem cells (MSCs) from the umbilical cord Wharton’s jelly scaffolds.
A Gärtner, T Pereira, R Gomes, I Amorim, J Ribeiro, ML França, S Geuna, AS Varejão, MA Lopes, JD Santos, AL Luís, AC Maurício
16:15 – 17:15 – COFFEE BREAK & POSTER VIEWING
17:15 – 17:55
PLENARY LECTURE III
Chair: Gustavo Tiscornia
Novel Gene Therapy Approaches in Fanconi Anemia
Juan A. Bueren – Hematopoietic Gene Therapy Division.CIEMAT/CIBER of Rare Diseases, Madrid, Spain
17:55 – 19:15 – SESSION 3. Regenerative Medicine
Chair: Ana Colete Maurício and José Bragança
17:55 – 18:20
INVITED SPEAKER 5 – Joana Paredes – IPATIMUP
Stem Cells and Cancer: a challenging crosstalk for Regenerative Medicine
Joana Paredes
18:20 – 18:45
INVITED SPEAKER 6 – Gustavo Tiscornia – UALG/CBME
Disease Modelling the Neuropathic Form of Gaucher’s Disease Using Induced Pluripotent Stem Cells
Gustavo Tiscornia
18:45 – 19:00
Injectable bone substitute based on Bonelike® granules and a bioactive and antimicrobial hydrogel
DS Morais, MA Rodrigues, TI Silva, MA Lopes, M Santos, MJ Coelho, MP Ferraz, JD Santos, CM Botelho
19:00 – 19:15
A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells
R Cecchelli, S Aday, E Sevin, C Almeida, M Culot, L Dehouck, C Coisne, B Engelhardt, MP Dehouck, R Langer, L Ferreira
9:30 – 10:10
PLENARY LECTURE IV
Chair: Rui L. Reis
Building Tissue High Throughput
Clemens van Blitterswijk – MIRA institute, University of Twente, Netherlands
10:10 – 12:15 - SESSION 4. Stem Cell Toolbox
Chair: Susana Solá and João Mano
10:10 – 10:35
INVITED SPEAKER 7 – Alexandra P. Marques – UMinho/3B’s
Stem cells contribution to epidermis morphogenesis
Alexandra P. Marques
10:35 – 11:05 – COFFEE BREAK
11:05 – 11.30
INVITED SPEAKER 8 – Lino S. Ferreina – BIOCANT/CNC
Controlling stem cell activity by nanomaterials
Lino S. Ferreira
11:30 – 11:45
Ontogenic-specific Extracellular Matrix: A niche for Heart Regeneration
AC Silva, DS Nascimento, MJ Oliveira, MA Barbosa, P Pinto-do-Ó
11:45 – 12:00
Locust Bean Gum and Pullulan polymeric coatings for embryonic stem cell culture
AR Perestrelo, A Grenha, AMR da Costa, JA Belo
12:00 – 12:15
Functionalized microgels for controlled stem cell proliferation and differentiation
CA Custódio, VE Santo, MB Oliveira, ME Gomes, RL Reis, JF Mano
12:15 – 13:00 – POSTER VIEWING
14:30 – 15:10
PLENARY LECTURE V
Chair: Joaquim S. Cabral
Development of a perfusion bioreactor for the physiological culture and targeted differentiation of embryonic stem cells
Sakis Mantalaris - Centre for Process Systems Engineering, Imperial College London, UK.
15:10 – 16:45 – SESSION 5. Stem Cell Bioprocessing
Chair: Joana Miranda and Pedro Granja
15:10 – 15:35
INVITED SPEAKER 9 – Maria Margarida Diogo – IST/IBB
Evaluation of microcarrier-based suspension cultures for human induced pluripotent stem cells
Sara M. Badenes, Tiago G. Fernandes, Annette Pusch, Simone Haupt, Carlos A.V. Rodrigues, Marie-Maud Bear, Martial Hervy, Maria Margarida Diogo, Oliver Brüstle, and Joaquim M.S. Cabral
15:35 – 16:00
INVITED SPEAKER 10 – Margarida Serra – ITQB/UNL/IBET
Robust cell manufacturing platforms and novel proteomic approaches to streamline the design of cell-based therapies for myocardial infartion
Margarida Serra, C. Correia, P. Gomes-Alves, M. Sousa, C. Brito, K. Burkert, J. Hescheler, T Saric, LB Rodriguez, JA López, J Vazquez, A Bernad, MJT Carrondo, PM Alves
16:00 – 16:15
A two-phase protocol for the expansion and megakaryocytic differentiation of umbilical cord blood hematopoietic stem/progenitor cells
J Hatami, PZ Andrade, JMS Cabral, CL da Silva, F Castelo Ferreira
16:15 – 16:30
Novel human 3D cell models for neurotoxicity studies
AP Terrasso, M Serra, AE Filipe, AL Ferreira, P Pedroso P, Alves PM, Brito C
16:45 – 17:15 – COFFEE BREAK
17:15 – 18:15 – GENERAL ASSEMBLY
18:15 – 18:45 – CLOSING SESSION
